EDAX quantitation of phosphorus is an objective biomarker for psoriatic disease activity and treatment response

Authors

DOI:

https://doi.org/10.46570/utjms-2026-1898

Keywords:

psoriasis, phosphorus, objective testing, energy dispersive x ray microanalysis, electron transmission microscopy

Abstract

Assessing the effectiveness of newer treatments of psoriasis continue to be analyzed by various clinical parameters. Such evaluations include psoriasis area and severity index (PAPS), body surface area (BSA), dermatology life quality index (DLQI), physician's global assessment (PGA), self-administered PASI (SAPASI), and psoriasis epidemiology screening tool (PEST). Of note, there are few objective tests for use in determining treatment response with psoriasis.  Of all the objective tests discussed, energy dispersive x-ray microanalysis quantitates and localizes the element to the tissue studied and moreover could act as an objective test to act as a biomarker for psoriatic activity and treatment response.

Author Biography

Dr. Craig Burkhart, MD, MPH, Clinical Professor, Department of Medicine

Professional Background
  • Specialty: Medical Dermatology (skin cancer checks, biopsies, rashes, eczema)
  • Education: Earned his medical degree from the University of Toledo College of Medicine (formerly Medical College of Ohio).
  • Academic Role: Clinical Professor at UToledo and Clinical Assistant Professor at Ohio University.

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Cover of Translation: The University of Toledo Journal of Medical Sciences, Volume 16, Issue 2 (2026). The cover features a layered green collage design with the journal title "Translation" in large tan lettering across the top and the full journal name set within a darker green panel. The central artwork shows three overlapping human silhouettes in cream, tan, and brown tones layered with circular medical imaging insets - an ultrasound image and a chest radiograph. A gold DNA double helix runs vertically along the right edge, and a honeycomb hexagonal pattern textures the background, with the volume and issue designation ("Vol. 16, No. 2 (2026)") displayed in a rounded tan banner in the lower right corner.

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Published

2026-10-28

How to Cite

1.
Burkhart C. EDAX quantitation of phosphorus is an objective biomarker for psoriatic disease activity and treatment response. Translation [Internet]. 2026 Oct. 28 [cited 2026 Oct. 30];16(2). Available from: https://openjournals.utoledo.edu/index.php/translation/article/view/1898

Issue

Vol. 16 No. 2 (2026): Volume 16, (2026)

Section

Miscellaneous

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Copyright (c) 2026 Dr. Craig Burkhart, MD, MPH (Author)

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