Untreated HSV Leading to Neonatal Death

Authors

DOI:

https://doi.org/10.46570/utjms-2024-852

Keywords:

neonatal sepsis, HSV sepsis, neonatal death, post-partum HSV

Abstract

We discuss a case of a 10-day-old infant who presented in fulminant early-onset sepsis due to HSV (Herpes Simplex Virus), the patient ultimately succumbed to illness due to septic shock. The patient’s mother received a diagnosis of HSV in the days following delivery. However, without a system in place to connect a maternal diagnosis to the infant, the baby was not treated empirically. We discuss the early signs and symptoms of neonatal sepsis, including those that were present in this patient. Further emphasis is placed on
the importance of early detection and prompt treatment of HSV sepsis due to the high mortality rate of the disease, including the potential need for a notification system to inform pediatricians and family practitioners about maternal post-partum diagnoses.

References

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and in neonate: status of art of epidemiology, diagnosis, therapy and prevention. Virol J, 2009. 6, 40. https://doi.org/10.1186/1743-422X-6-40

(2) Straface, G., Selmin, A., Zanardo, V., De Santis, M., Ercoli, A., Scambia, G. Herpes

Simplex Virus Infection in Pregnancy. Infect Dis Obstet Gynecol, 2012.

1155/2012/385697

(3) Shane, A., Sanchez, P., Stoll, B. Neonatal Sepsis. Lancet, 2017. 390: 1770-1780.

http://dx.doi.org/10.1016/S0140-6736(17)31002-4

(4) Bachtiar, K., Oswari, H., Batubara, J., Amir, I., Latief, A., Firman, K. Cholestasis sepsis

at neonatology ward and neonatal ICU Cipto Mangunkusumo Hospital 2007: incidence, mortality rate, and associated risk factors. Cholestasis sepsis in neonates, 2008. 17(2): 107-113.

(5) Mahmud, S., Sarma, M., Darma, A., Ahmed, S. Neonatal Cholestasis: An Update.

Gastroenterology and Hepatology, 2021. 12(2): 54-66.

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Published

2025-02-04

How to Cite

Sawyer, M., & Thomas, S. (2025). Untreated HSV Leading to Neonatal Death. Translation: The University of Toledo Journal of Medical Sciences, 13(1). https://doi.org/10.46570/utjms-2024-852

Issue

Vol. 13 No. 1 (2024)

Section

Case Reports

License

Copyright (c) 2024 Meghan Sawyer, Dr. Sharon Thomas (Author)

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