Primary Pure Angiosarcoma of the Testis: A Case Report

Authors

  • Samay Jain The University of Toledo
  • Richard Cantley University of Toledo Medical Center
  • Justus Philip University of Toledo College of Medicine and Life Sciences

DOI:

https://doi.org/10.46570/utjms.vol1-2014-82

Keywords:

Testicle, Angiosarcoma, germ cell tumor, testicular neoplasm, sarcoma

Abstract

Angiosarcoma is a rare and aggressive, malignant neoplasm of endothelial-cell origin.   A primary angiosarcoma originating in the testicle is extremely rare, with only five previous cases reported in the current literature. We report a case of primary, pure angiosarcoma of the testis in a 63-year-old patient with no history of previous chemotherapy or radiation therapy. By histology, the tumor was a high-grade spindle cell neoplasm, arranged in sheets and poorly-formed vascular channels. The tumor cells were positive for vascular markers (CD31, CD34) by immunohistochemical staining. No evidence of a germ cell component was seen by morphology, immunohistochemistry, or molecular genetic studies. This finding is unique in that it is one of only three reported cases of primary angiosarcomas of the testicle without a germ cell precursor or component.

Author Biographies

Samay Jain, The University of Toledo

Department of Urology

Assistant Professor, Division Chief, Urologic Oncology, & Medical Director of the Urology Clinic

 

Richard Cantley, University of Toledo Medical Center

Department of Pathology

Assistant Professor

Justus Philip, University of Toledo College of Medicine and Life Sciences

Department of Pathology: Pre-clinical Pathology Student Fellow (2013-2014)

 

References

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Published

2014-06-30

How to Cite

Jain, S., Cantley, R., & Philip, J. (2014). Primary Pure Angiosarcoma of the Testis: A Case Report. Translation: The University of Toledo Journal of Medical Sciences, 1(1), C 1–3. https://doi.org/10.46570/utjms.vol1-2014-82

Issue

Vol. 1 (2014): Volume 1, 2014

Section

Case Reports

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