Comorbidities associated with Sjögren's syndrome: Results from the Nationwide Inpatient Sample.

Authors

  • Terah Koch Nationwide Children's Hospital, Columbus, OH 43205
  • Ibtisam Al-Hashimi Texas A&M University Baylor College of Dentistry, Dallas, TX 75246
  • Boyd M. Koffman Department of Neurology, University of Toledo Health Science Campus, Toledo, OH 43614
  • Abhishek Deshpande Case Western Reserve University School of Medicine, Cleveland OH 44106
  • Sadik A. Khuder University of Toledo Health Science Campus, Toledo, OH 43614

DOI:

https://doi.org/10.46570/utjms.vol1-2014-74

Keywords:

Sjögren’s syndrome, autoimmune diseases, comorbidities, HCUP data

Abstract

Although multiple comorbidities associated with Sjögren’s syndrome (SS) have been reported, reliable data regarding the prevalence of specific comorbidities among patients with SS remain sparse. In this study, we investigated the prevalence and risk for a broad spectrum of medical conditions among patients with SS in the United States. The Health Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) data was utilized in order to investigate 29 different comorbidities among SS patients. Between the years 2007 to 2009 there were 19,127 admissions with SS listed as principal diagnosis (1.3%) and secondary diagnosis (98.7%). Compared with 57,381 controls, SS patients had significantly higher prevalence of lymphoma (OR 1.6), valvular disease (OR 1.42), congestive heart failure (OR 1.28), hypothyroidism (OR 1.24), paralysis (OR 1.24), deficiency anemia (OR 1.16), depression (OR 1.18), neurological disorders (OR 1.17), and chronic pulmonary disease (OR 1.07). SS is associated with substantial medical conditions that may impact morbidity and mortality as well as quality of life for individuals suffering from SS.

Author Biographies

Terah Koch, Nationwide Children's Hospital, Columbus, OH 43205

Research Associate

Ibtisam Al-Hashimi, Texas A&M University Baylor College of Dentistry, Dallas, TX 75246

Professor, Department of Periodontics

Boyd M. Koffman, Department of Neurology, University of Toledo Health Science Campus, Toledo, OH 43614

Professor, Department of Neurology

Abhishek Deshpande, Case Western Reserve University School of Medicine, Cleveland OH 44106

Department of medicine

Sadik A. Khuder, University of Toledo Health Science Campus, Toledo, OH 43614

Professor, Department of Medicine

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Published

2014-04-02

How to Cite

Koch, T., Al-Hashimi, I., Koffman, B. M., Deshpande, A., & Khuder, S. A. (2014). Comorbidities associated with Sjögren’s syndrome: Results from the Nationwide Inpatient Sample. Translation: The University of Toledo Journal of Medical Sciences, 1(1), 4–7. https://doi.org/10.46570/utjms.vol1-2014-74

Issue

Vol. 1 (2014): Volume 1, 2014

Section

Research Articles

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