Streptococcus Intermedius Lung Abscess in a 17-year-old Male

Authors

  • Jason Andrew Levine University of Toledo
  • Karen Hovsepyan University of Toledo Pediatrics
  • Daniel Lubarsky University of Toledo College of Medicine
  • Deepa Mukundan University of Toledo Pediatrics
  • Jennifer Ruddy ProMedica Toledo Children's Hospital

DOI:

https://doi.org/10.46570/utjms.vol6-2019-318

Keywords:

marijuana, vapingsmoking, intermedius, empyema

Abstract

Streptococcus intermedius lung abscess and empyema is a chronic infectious process associated with a high morbidity and mortality.  It is typically seen in adults, and is considered a rare disease process in the pediatric population.  Our case describes a 17 year old male presenting with 3 months of cough associated with later development of chest and back pain.  He was later found to have a severe empyema secondary to Streptococcus intermedius.  This case underlines a rare diagnosis in the pediatric population, as well as a association with smoking and vaping. 

Author Biographies

Jason Andrew Levine, University of Toledo

University of Toledo Pediatrics, PGY-3

Karen Hovsepyan, University of Toledo Pediatrics

University of Toledo Pediatrics, PGY-3

Daniel Lubarsky, University of Toledo College of Medicine

3rd Year Medical Student

Deepa Mukundan, University of Toledo Pediatrics

Associate Professor of Pediatrics, Infectious Diseases Chief, Clerkship Director

Jennifer Ruddy, ProMedica Toledo Children's Hospital

Pediatric Pulmonologist, Assistant Professor of Pediatrics, Co-Director of Cystic Fibrosis Center

References

Bibliography

WHILEY, R. A. et al. Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus (the Streptococcus milleri group): association with different body sites and clinical infections. J Clin Microbiol, v. 30, n. 1, p. 243-4, Jan 1992. ISSN 0095-1137 (Print) DOI: https://doi.org/10.1128/jcm.30.1.243-244.1992

-1137 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/1734062 >.

WHILEY, R. A.; BEIGHTON, D. Emended descriptions and recognition of Streptococcus constellatus, Streptococcus intermedius, and Streptococcus anginosus as distinct species. Int J Syst Bacteriol, v. 41, n. 1, p. 1-5, Jan 1991. ISSN 0020-7713 (Print) DOI: https://doi.org/10.1099/00207713-41-1-1

-7713 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/1995029 >.

WHILEY, R. A. et al. Phenotypic differentiation of Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus strains within the "Streptococcus milleri group". J Clin Microbiol, v. 28, n. 7, p. 1497-501, Jul 1990. ISSN 0095-1137 (Print) DOI: https://doi.org/10.1128/jcm.28.7.1497-1501.1990

-1137 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/2380375 >.

GIDDINGS, K. S. et al. Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nat Struct Mol Biol, v. 11, n. 12, p. 1173-8, Dec 2004. ISSN 1545-9993 (Print) DOI: https://doi.org/10.1038/nsmb862

-9985 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/15543155 >.

NAGAMUNE, H. et al. The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein. Microbiol Immunol, v. 48, n. 9, p. 677-92, 2004. ISSN 0385-5600 (Print) DOI: https://doi.org/10.1111/j.1348-0421.2004.tb03479.x

-5600 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/15383705 >.

BANTAR, C. et al. Species belonging to the "Streptococcus milleri" group: antimicrobial susceptibility and comparative prevalence in significant clinical specimens. J Clin Microbiol, v. 34, n. 8, p. 2020-2, Aug 1996. ISSN 0095-1137 (Print) DOI: https://doi.org/10.1128/jcm.34.8.2020-2022.1996

-1137 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/8818904 >.

CLARIDGE, J. E., 3RD et al. Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus ("Streptococcus milleri group") are of different clinical importance and are not equally associated with abscess. Clin Infect Dis, v. 32, n. 10, p. 1511-5, May 15 2001. ISSN 1058-4838 (Print) DOI: https://doi.org/10.1086/320163

-4838 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/11317256 >.

YOUNG, K. A. et al. Interactions between Eikenella corrodens and 'Streptococcus milleri-group' organisms: possible mechanisms of pathogenicity in mixed infections. Antonie Van Leeuwenhoek, v. 69, n. 4, p. 371-3, May 1996. ISSN 0003-6072 (Print) DOI: https://doi.org/10.1007/BF00399626

-6072 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/8836435 >.

JERNG, J. S. et al. Empyema thoracis and lung abscess caused by viridans streptococci. Am J Respir Crit Care Med, v. 156, n. 5, p. 1508-14, Nov 1997. ISSN 1073-449X (Print) DOI: https://doi.org/10.1164/ajrccm.156.5.97-03006

-449X (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/9372668 >.

WARGO, K. A.; MCCONNELL, V. J.; HIGGINBOTHAM, S. A. A case of Streptococcus intermedius empyema. Ann Pharmacother, v. 40, n. 6, p. 1208-10, Jun 2006. ISSN 1060-0280 (Print) DOI: https://doi.org/10.1345/aph.1G704

-0280 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/16735670 >.

NOGUCHI, S. et al. The clinical features of respiratory infections caused by the Streptococcus anginosus group. BMC Pulm Med, v. 15, p. 133, Oct 26 2015. ISSN 1471-2466 (Electronic) DOI: https://doi.org/10.1186/s12890-015-0128-6

-2466 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/26502716 >.

FADEN, H. S. Infections Associated with Streptococcus intermedius in Children. Pediatr Infect Dis J, v. 35, n. 9, p. 1047-8, Sep 2016. ISSN 1532-0987 (Electronic) DOI: https://doi.org/10.1097/INF.0000000000001227

-3668 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/27294306 >.

BELKO, J. et al. Clinically significant infections with organisms of the Streptococcus milleri group. Pediatr Infect Dis J, v. 21, n. 8, p. 715-23, Aug 2002. ISSN 0891-3668 (Print) DOI: https://doi.org/10.1097/00006454-200208000-00002

-3668 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/12192158 >.

WENZLER, E. et al. Clinical and microbiological outcomes in patients with Streptococcus anginosus group bacteraemia identified through use of a rapid microarray assay. J Med Microbiol, v. 64, n. 11, p. 1369-74, Nov 2015. ISSN 1473-5644 (Electronic) DOI: https://doi.org/10.1099/jmm.0.000176

-2615 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/26408191 >.

BAGAITKAR, J.; DEMUTH, D. R.; SCOTT, D. A. Tobacco use increases susceptibility to bacterial infection. Tob Induc Dis, v. 4, p. 12, Dec 18 2008. ISSN 1617-9625 (Electronic) DOI: https://doi.org/10.1186/1617-9625-4-12

-9625 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/19094204 >.Disponível em: < https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628337/pdf/1617-9625-4-12.pdf >.

KUMAR, A. N. et al. Marijuana "bong" pseudomonas lung infection: a detrimental recreational experience. Respirol Case Rep, v. 6, n. 2, p. e00293, Feb 2018. ISSN 2051-3380 (Print) DOI: https://doi.org/10.1002/rcr2.293

-3380 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/29321937 >.Disponível em: < https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756717/pdf/RCR2-6-e00293.pdf >.

SUSSAN, T. E. et al. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. PLoS One, v. 10, n. 2, p. e0116861, 2015. ISSN 1932-6203 (Electronic) DOI: https://doi.org/10.1371/journal.pone.0116861

-6203 (Linking). Disponível em: < https://www.ncbi.nlm.nih.gov/pubmed/25651083 >.

CATALYA, S., KOMAL, B., TULPULE, S., RAOOF, N., & SEN, S. (2017). Isolated Streptococcus intermedius pulmonary nodules. IDCases, 8, 48-49. doi:10.1016/j.idcr.2017.03.007 DOI: https://doi.org/10.1016/j.idcr.2017.03.007

Hameed, S., Singh, J., Tricia, L. B., Machado, A., Ruggieri, P., & Mehta, A. C. (2017). Conglomerate mediastinal mass of a different etiology. Oxf Med Case Reports, 2017(12), omx072. doi:10.1093/omcr/omx072 DOI: https://doi.org/10.1093/omcr/omx072

Editorial Cover for Volume 6, 2019

Downloads

Published

2019-12-03

How to Cite

Levine, J. A., Hovsepyan, K., Lubarsky, D., Mukundan, D., & Ruddy, J. (2019). Streptococcus Intermedius Lung Abscess in a 17-year-old Male. Translation: The University of Toledo Journal of Medical Sciences, 6, 11–14. https://doi.org/10.46570/utjms.vol6-2019-318

Issue

Vol. 6 (2019): Volume 6, 2019

Section

Case Reports

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).