Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation

Authors

  • Farah Karipineni
  • Afshin Parsikia Einsten Medical Center
  • PoNan Chang
  • John Pang
  • Stalin Campos
  • Kamran Khanmoradi
  • Radi Zaki
  • Jorge Ortiz

DOI:

https://doi.org/10.46570/utjms.vol10-2016-201

Abstract

Objectives:
Asians represent the fastest growing ethnic group in the United States. Despite significant diversity within the group, many transplant studies treat Asians as a homogeneous entity. We compared patient and graft survival among major Asian eth- nicities to determine whether any subgroup has superior out- comes.

Methods: We conducted a retrospective analysis of kidney trans- plants on Asian and White patients between 2001 and 2012. Co- variates included gender, age, comorbidities, and donor category. Primary outcomes included one-year patient and graft survival. Secondary outcomes included delayed graft function (DGF) and rejection as cause of graft loss and death.

Results: Ninety-one Asian patients were identified. Due to the large proportion of Chinese patients (n=37), we grouped other Asians into one entity (n=54) for statistical comparison among Chinese, other Asians, and Whites (n=346). Chinese subjects had significantly lower body mass index (BMI) (p=0.001) and had the lowest proportion of living donors (p>0.001). Patient survival was highest in our Chinese cohort (p>0.001)

Discussion: Our study confirms outcome differences among Asian subgroups in kidney transplantation. Chinese demonstrate better patient survival at one year than Whites and non-Chinese Asians despite fewer live donors. Lower BMI scores may partly explain this. Larger, long-term studies are needed to elucidate outcome disparities among Asian subgroups

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Published

2022-12-20

How to Cite

Karipineni, F., Parsikia, A., Chang, P., Pang, J., Campos, S., Khanmoradi, K., Zaki, R., & Ortiz, J. (2022). Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation. Translation: The University of Toledo Journal of Medical Sciences, 10(1), 5–9. https://doi.org/10.46570/utjms.vol10-2016-201

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Research Articles