Mind over Microbes
The Role of the Microbiota-Gut-Brain Axis in Depression and Anxiety
DOI:
https://doi.org/10.46570/utjms-2026-1681Keywords:
Microbiota-gut-brain-axis, Dysbiosis, Depression and anxietyReferences
Simpson CA, Diaz-Arteche C, Eliby D, Schwartz OS, Simmons JG, Cowan CSM. The gut microbiota in anxiety and depression - A systematic review. Clin Psychol Rev. 2021 Feb. doi: 10.1016/j.cpr.2020.101943. https://www.sciencedirect.com/science/article/abs/pii/S0272735820301318?via%3Dihub
Shaikh RG, Dey A, Singh VP, Khandagle A, M B, Naik S, Hasan A. Understanding the Impact of the Gut Microbiome on Mental Health: A Systematic Review. Cureus. 2025 Jan. doi: 10.7759/cureus. https://pmc.ncbi.nlm.nih.gov/articles/PMC11865252/
Wilson DR, Binford L, Hickson S. The Gut Microbiome and Mental Health. Journal of Holistic Nursing. 2023;42(1):79-87. doi:10.1177/08980101231170487. https://journals.sagepub.com/doi/full/10.1177/08980101231170487
Chudzik A, Orzy?owska A, Rola R, Stanisz GJ. Probiotics, Prebiotics and Postbiotics on Mitigation of Depression Symptoms: Modulation of the Brain-Gut-Microbiome Axis. Biomolecules. 2021 Jul. doi: 10.3390/biom11071000. https://pmc.ncbi.nlm.nih.gov/articles/PMC8301955/
Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota's effect on mental health: The gut-brain axis. Clin Pract. 2017 Sep. doi: 10.4081/cp.2017.987. https://pmc.ncbi.nlm.nih.gov/articles/PMC5641835/
Bhatt S, Kanoujia J, Mohana Lakshmi S, Patil CR, Gupta G, Chellappan DK, Dua K. Role of Brain-Gut-Microbiota Axis in Depression: Emerging Therapeutic Avenues. CNS Neurol Disord Drug Targets. 2023. doi: 10.2174/1871527321666220329140804. https://pubmed.ncbi.nlm.nih.gov/35352640/
Sonali S, Ray B, Ahmed Tousif H, Rathipriya AG, Sunanda T, Mahalakshmi AM, Rungratanawanich W, Essa MM, Qoronfleh MW, Chidambaram SB, Song BJ. Mechanistic Insights into the Link between Gut Dysbiosis and Major Depression: An Extensive Review. Cells. 2022 Apr. doi: 10.3390/cells11081362. https://pmc.ncbi.nlm.nih.gov/articles/PMC9030021/
Kumar A, Pramanik J, Goyal N, Chauhan D, Sivamaruthi BS, Prajapati BG, Chaiyasut C. Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. Pharmaceuticals (Basel). 2023 Apr. doi: 10.3390/ph16040565. https://pmc.ncbi.nlm.nih.gov/articles/PMC10146621/
Dziedzic A, Maciak K, Bli?niewska-Kowalska K, Ga?ecka M, Kobierecka W, Saluk J. The Power of Psychobiotics in Depression: A Modern Approach through the Microbiota-Gut-Brain Axis: A Literature Review. Nutrients. 2024 Apr. doi: 10.3390/nu16071054. https://pmc.ncbi.nlm.nih.gov/articles/PMC11013390/
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Fatimah Aftab, Sara Razoky, Sweta Desai (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
