Translation: The University of Toledo Journal of Medical Sciences

Translation: The University of Toledo Journal of Medical Sciences https://openjournals.utoledo.edu/index.php/translation Translation: The University of Toledo Journal of Medical Sciences is the online journal launched by the University of Toledo. Manuscripts will be considered on the understanding that they report original work and are not under consideration for publication by any other journal. The journal publishes original articles reporting experimental results of basic or clinical research, case reports, and reviews. The journal uses a single blind peer review system and each manuscript, based on the results presented in its original submission, will be evaluated by two student reviewers and one faculty reviewer. This process will provide an opportunity for medical students, graduate students, residents, fellows and faculty to publish research observation in a timely manner. Students should complete this <a href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fforms.office.com%2Fr%2F43Kuvszvm9&data=05%7C01%7CMargaret.Hoogland%40UToledo.edu%7Ce1cdc0822af94316fa8908dba7f6bbd1%7C1d6b1707baa94a3da8f8deabfb3d467b%7C0%7C0%7C638288450392831219%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=f%2BsoDajHkjRh0pSKoBP0HVnzxATJ3gsstCJ8VmnPSeo%3D&reserved=0">form</a> to become a reviewer! ISSN: 2469-6706 <a title="Visit the journal's landing page" href="https://doi.org/10.46570/utjms.2469-6706">DOI: 10.46570/utjms.2469-6706</a> en-US Authors who publish with this journal agree to the following terms: <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a title="Creative Commons License: Attribution 4.0 International (CC BY 4.0)" href="https://creativecommons.org/licenses/by/4.0/" target="_blank" rel="noopener">Creative Commons Attribution License (CC BY 4.0)</a> that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See <a title="The effect of open access and downloads ('hits') on citation impact: a bibliography of studies" href="http://opcit.eprints.org/oacitation-biblio.html" target="_blank" rel="noopener">The Effect of Open Access</a>).</li> </ol> translation@utoledo.edu (Robert Mccullumsmith M.D., Ph.D.) arjun.sabharwal@utoledo.edu (Arjun Sabharwal, MA., MLIS) Wed, 15 Oct 2025 15:54:05 +0000 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Gut Microbiota Modulation: Akkermansia muciniphila Lowers Blood Pressure by Restoring Serotonergic Gut-Vagal Signaling in Rodents https://openjournals.utoledo.edu/index.php/translation/article/view/1485 Hemaa Sree Kumar, Sarah Alekhtiar, Emily Otmanowski, Adriana Alviter Plata, Nicole Bearss, Rohit Shukla, Dhananhay Yadav, Vivek Kumar, Mia GB Consortium, Shalini Jain, Guillaume De Lartigue, Jasenka Zubcevic (Author) Copyright (c) 2025 Hemaa Sree Kumar, Sarah Alekhtiar, Emily Otmanowski, Adriana Alviter Plata, Nicole Bearss, Rohit Shukla, Dhananhay Yadav, Vivek Kumar, Mia GB Consortium, Shalini Jain, Guillaume De Lartigue, Jasenka Zubcevic (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1485 Wed, 15 Oct 2025 00:00:00 +0000 Management of Severe Anorexia Nervosa: A Case Report https://openjournals.utoledo.edu/index.php/translation/article/view/1504 Nilan Mani, Sabrina Khuder, Jeffrey Boward, Victoria Kelly (Author) Copyright (c) 2025 Nilan Mani, Sabrina Khuder, Jeffrey Boward, Victoria Kelly (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1504 Wed, 15 Oct 2025 00:00:00 +0000 Folate prevent autism-relevant phenotype from developmental pyrethroid exposure in Prarie Voles https://openjournals.utoledo.edu/index.php/translation/article/view/1524 Nilanjana Saferin, Radha Shah Shah (Author) Copyright (c) 2025 Nilanjana Saferin, Radha Shah Shah (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1524 Wed, 15 Oct 2025 00:00:00 +0000 Unraveling the Gut: A Case of Adult-Onset Avoidant Restrictive Food Intake Disorder Related To Chronic GI Issues https://openjournals.utoledo.edu/index.php/translation/article/view/1492 Connor Segur, Felix Griffin, Blair Hermiller, MD, Victoria Kelly, MD (Author) Copyright (c) 2025 Connor Segur, Felix Griffin, Blair Hermiller, MD, Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1492 Wed, 15 Oct 2025 00:00:00 +0000 Investigating the Symptom Profile of Depression and Validity of Psychological Assessments in the South Asian Population https://openjournals.utoledo.edu/index.php/translation/article/view/1480 Nithara Murthy, Global Health (BA); Psychology (BS), Dr. Victoria Kelly, MD, Manasa Swaminathan, Psychology (BS); Clinical Psychology (MS) (Author) Copyright (c) 2025 Nithara Murthy, Global Health (BA); Psychology (BS), Dr. Victoria Kelly, MD, Manasa Swaminathan, Psychology (BS); Clinical Psychology (MS) (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1480 Wed, 15 Oct 2025 00:00:00 +0000 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and synaptic plasticity in mouse brain https://openjournals.utoledo.edu/index.php/translation/article/view/1483 Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith, James P. Burkett (Author) Copyright (c) 2025 Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith, James P. Burkett (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1483 Wed, 15 Oct 2025 00:00:00 +0000 Pathway enrichment and FDA-approved drug repurposing analysis for the treatment of CTNNB1 Syndrome modeled in an SH-SY5Y cell line https://openjournals.utoledo.edu/index.php/translation/article/view/1507 John Vergis, Robert E. McCullumsmith (Author) Copyright (c) 2025 John Vergis, Robert E. McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1507 Wed, 15 Oct 2025 00:00:00 +0000 When PHACES hide faces: A Case Report of PHACE Syndrome with Depression https://openjournals.utoledo.edu/index.php/translation/article/view/1490 Isaac Arefi, Anish Sharma, Jessica Sedlak, Andrew Michaelis, Navtej Mann, Nilan Mani, Harmandeep Pannu, Tanvir Singh (Author) Copyright (c) 2025 Isaac Arefi, Anish Sharma, Jessica Sedlak, Andrew Michaelis, Navtej Mann, Nilan Mani, Harmandeep Pannu, Tanvir Singh (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1490 Wed, 15 Oct 2025 00:00:00 +0000 Naloxone Decriminalization and Opioid Overdose Trends: A Comparative Study of Lucas County, Ohio and the U.S. https://openjournals.utoledo.edu/index.php/translation/article/view/1512 Margarita Kugotova, Megan Kussman, Savanna King, Amber Edson, Mackenzie Hagood, Virinder Grewal, Tanvir Singh (Author) Copyright (c) 2025 Margarita Kugotova, Megan Kussman, Savanna King, Amber Edson, Mackenzie Hagood, Virinder Grewal, Tanvir Singh (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1512 Wed, 15 Oct 2025 00:00:00 +0000 I Got My Patient Arrested https://openjournals.utoledo.edu/index.php/translation/article/view/1496 Adam Koenig, MD, Jack Mariani, Mirlinda Elmazi, MD, Asif Becher, MD, Victoria Kelly, MD (Author) Copyright (c) 2025 Adam Koenig, MD, Jack Mariani, Mirlinda Elmazi, MD, Asif Becher, MD, Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1496 Wed, 15 Oct 2025 00:00:00 +0000 Dysregulation of insulin signaling pathways in schizophrenia https://openjournals.utoledo.edu/index.php/translation/article/view/1520 Sean Hanna, Abdul-Rizaq Hamoud, Laura Stertz, Ali S. 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McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1520 Wed, 15 Oct 2025 00:00:00 +0000 Using iLINCS to mine for Oxytocin signature to find new drug candidates or molecular pathways that can be used for future treatment for autism https://openjournals.utoledo.edu/index.php/translation/article/view/1486 Gabby, Elissar Andari (Author) Copyright (c) 2025 Gabby, Elissar Andari (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1486 Wed, 15 Oct 2025 00:00:00 +0000 Behavioral Disturbance in Polymicrogyria: Medication Management to Improve Quality of Life https://openjournals.utoledo.edu/index.php/translation/article/view/1476 Amanda Springer MD, Jack Mariani BS, Kayla Spradley DO, Kristi Williams MD (Author) Copyright (c) 2025 Amanda Springer MD, Jack Mariani BS, Kayla Spradley DO, Kristi Williams MD (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1476 Wed, 15 Oct 2025 00:00:00 +0000 The Change in Overall Sleep Quality before and after COVID-19 Pandemic due to COVID-19 Related Family Economic Strain and Social Interactions https://openjournals.utoledo.edu/index.php/translation/article/view/1502 Rupesh Boddapati, Jessica Zhukivska, Rowaida Hamdan, Dr. Xin Wang, Dr. Hong Xie (Author) Copyright (c) 2025 Rupesh Boddapati, Jessica Zhukivska, Rowaida Hamdan, Dr. Xin Wang, Dr. Hong Xie (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1502 Wed, 15 Oct 2025 00:00:00 +0000 Identifying Repurposable Drugs for Schizophrenia using Transcriptomic Datasets https://openjournals.utoledo.edu/index.php/translation/article/view/1521 Roshan Sirole, Ali Imami, Robert McCullumsmith (Author) Copyright (c) 2025 Roshan Sirole, Ali Imami, Robert McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1521 Wed, 15 Oct 2025 00:00:00 +0000 Transcranial Magnetic Stimulation for Substance Use Disorders https://openjournals.utoledo.edu/index.php/translation/article/view/1519 Smita Sahay, Madhu Rami Reddy, Robert McCullumsmith (Author) Copyright (c) 2025 Smita Sahay, Madhu Rami Reddy, Robert McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 https://openjournals.utoledo.edu/index.php/translation/article/view/1519 Wed, 15 Oct 2025 00:00:00 +0000 Designing an Elective Psychodynamic Curriculum for Medical Students https://openjournals.utoledo.edu/index.php/translation/article/view/1474 Jack Mariani, Robert McCullumsmith, Sweta Desai, Julia Dillard, Angad "Josh" Pelia, T. 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