Translation: The University of Toledo Journal of Medical Sciences https://openjournals.utoledo.edu/index.php/translation <p><em><strong>Translation: The University of Toledo Journal of Medical Sciences</strong></em> is the online journal launched by the University of Toledo. Manuscripts will be considered on the understanding that they report original work and are not under consideration for publication by any other journal. The journal publishes original articles reporting experimental results of basic or clinical research, case reports, and reviews.</p> <p>The journal uses a single blind peer review system and each manuscript, based on the results presented in its original submission, will be evaluated by two student reviewers and one faculty reviewer.</p> <p>This process will provide an opportunity for medical students, graduate students, residents, fellows and faculty to publish research observation in a timely manner.</p> <p>Students should complete this <a href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fforms.office.com%2Fr%2F43Kuvszvm9&amp;data=05%7C01%7CMargaret.Hoogland%40UToledo.edu%7Ce1cdc0822af94316fa8908dba7f6bbd1%7C1d6b1707baa94a3da8f8deabfb3d467b%7C0%7C0%7C638288450392831219%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&amp;sdata=f%2BsoDajHkjRh0pSKoBP0HVnzxATJ3gsstCJ8VmnPSeo%3D&amp;reserved=0">form</a> to become a reviewer!</p> <p>ISSN: 2469-6706 </p> <p><a title="Visit the journal's landing page" href="https://doi.org/10.46570/utjms.2469-6706">DOI: 10.46570/utjms.2469-6706</a></p> The University of Toledo en-US Translation: The University of Toledo Journal of Medical Sciences 2469-6706 <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a title="Creative Commons License: Attribution 4.0 International (CC BY 4.0)" href="https://creativecommons.org/licenses/by/4.0/" target="_blank" rel="noopener">Creative Commons Attribution License (CC BY 4.0)</a> that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See <a title="The effect of open access and downloads ('hits') on citation impact: a bibliography of studies" href="http://opcit.eprints.org/oacitation-biblio.html" target="_blank" rel="noopener">The Effect of Open Access</a>).</li> </ol> Dysregulation of insulin signaling pathways in schizophrenia https://openjournals.utoledo.edu/index.php/translation/article/view/1520 Sean Hanna Abdul-Rizaq Hamoud Laura Stertz Ali S. Imami William G. Ryan V Nicole Bearss Consuelo Walss-Bass Robert E. McCullumsmith Copyright (c) 2025 Sean Hanna, Abdul-Rizaq Hamoud, Laura Stertz, Ali S. Imami, William G. Ryan V, Nicole Bearss, Consuelo Walss-Bass, Robert E. McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1520 Using iLINCS to mine for Oxytocin signature to find new drug candidates or molecular pathways that can be used for future treatment for autism https://openjournals.utoledo.edu/index.php/translation/article/view/1486 Christopher (Gabby) Vento Elissar Andari Copyright (c) 2025 Gabby, Elissar Andari (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1486 Behavioral Disturbance in Polymicrogyria: Medication Management to Improve Quality of Life https://openjournals.utoledo.edu/index.php/translation/article/view/1476 Amanda Springer MD Jack Mariani BS Kayla Spradley DO Kristi Williams MD Copyright (c) 2025 Amanda Springer MD, Jack Mariani BS, Kayla Spradley DO, Kristi Williams MD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1476 The Change in Overall Sleep Quality before and after COVID-19 Pandemic due to COVID-19 Related Family Economic Strain and Social Interactions https://openjournals.utoledo.edu/index.php/translation/article/view/1502 Rupesh Boddapati Jessica Zhukivska Rowaida Hamdan Xin Wang Hong Xie Copyright (c) 2025 Rupesh Boddapati, Jessica Zhukivska, Rowaida Hamdan, Dr. Xin Wang, Dr. Hong Xie (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1502 Identifying Repurposable Drugs for Schizophrenia using Transcriptomic Datasets https://openjournals.utoledo.edu/index.php/translation/article/view/1521 Roshan Sirole Ali Imami Robert McCullumsmith Copyright (c) 2025 Roshan Sirole, Ali Imami, Robert McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1521 Transcranial Magnetic Stimulation for Substance Use Disorders https://openjournals.utoledo.edu/index.php/translation/article/view/1519 Smita Sahay Madhu Rami Reddy Robert McCullumsmith Copyright (c) 2025 Smita Sahay, Madhu Rami Reddy, Robert McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1519 Designing an Elective Psychodynamic Curriculum for Medical Students https://openjournals.utoledo.edu/index.php/translation/article/view/1474 Jack Mariani Robert McCullumsmith Sweta Desai Julia Dillard Angad "Josh" Pelia T. Nicholas Domitrovic Copyright (c) 2025 Jack Mariani, Robert McCullumsmith, Sweta Desai, Julia Dillard, Angad "Josh" Pelia, T. Nicholas Domitrovic (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1474 Exploring Phosphatase Targets in Alzheimer's Disease: A Comprehensive Sequence and Gene Expression Analysis https://openjournals.utoledo.edu/index.php/translation/article/view/1526 Kayden Cuneo William Ryan Sean Hanna Ali Imani Robert McCullumsmith Copyright (c) 2025 Kayden Cuneo, William G. Ryan V, Sean Hanna, Ali Imani, Robert McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1526 Feasting on Flesh https://openjournals.utoledo.edu/index.php/translation/article/view/1510 Sarah Porter Alyssa Davis Dominique Digiacomo Michelle Cherian Navtej Mann Garrett Spradley Victoria Kelly Copyright (c) 2025 Sarah Porter, Alyssa Davis, Dominique Digiacomo, Michelle Cherian, Dr. Navtej Mann, Dr. Garrett Spradley, Dr. Victoria Kelly (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1510 Obstetric Outcomes and Effects from COL6A3-Associated-Bethlem Myopathy: A Case Report https://openjournals.utoledo.edu/index.php/translation/article/view/1499 Ajay Nair B.A. Ajay Nair Sabeena Malik M.D. James Van Hook M.D Copyright (c) 2025 Ajay Nair B.A. Ajay Nair, Sabeena Malik M.D., James Van Hook M.D (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1499 Structural Analysis of Hippocampal Subdivisions and Their Relationship with the Hypothalamus in Trauma Survivors https://openjournals.utoledo.edu/index.php/translation/article/view/1500 Rowaida Hamdan Chia-Hao Shih Qin Shao Xin Wang Hong Xie Copyright (c) 2025 Rowaida Hamdan, Chia-Hao Shih, Qin Shao, Xin Wang, Hong Xie (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1500 Asymmetry in Parkinson’s Disease: Exploring the Role of Hemispheric Specialization in Treatment Success https://openjournals.utoledo.edu/index.php/translation/article/view/1475 Dipesh Pokharel Caroline Swain Dilshan Beligala Isable Nester Khoi Le Vaibhavi Peshattiwar Kala Venkiteswaran Thyagarajan Subramanian Copyright (c) 2025 Dipesh Pokharel, Caroline Swain , Dilshan Beligala, Isable Nester , Khoi Le , Vaibhavi Peshattiwar, Kala Venkiteswaran , Thyagarajan Subramanian (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1475 National Trends on Chief Resident Salaries Across the United States https://openjournals.utoledo.edu/index.php/translation/article/view/1501 Chelsea Myles, MD Gregory Everett, MD Eric Gao, DO Victoria Kelly, MD Copyright (c) 2025 Chelsea Myles, MD, Gregory Everett, MD, Eric Gao, DO, Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1501 Rhabdomyolysis in a Patient with Polysubstance Use Disorder: A Case Report of Intentional Caffeine Intoxication https://openjournals.utoledo.edu/index.php/translation/article/view/1473 Lisa Zhang Eric Southard Amrit Bhatia Navtej Mann Robert Smith Copyright (c) 2025 Lisa Zhang, Eric Southard, Amrit Bhatia, Navtej Mann, Robert Smith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1473 Biphasic Onset of Spinal Epidural Hematoma: A Diagnostic Challenge https://openjournals.utoledo.edu/index.php/translation/article/view/1488 Brianna Bailey Daniel Branch Aditya Acharya Clayton Buback Copyright (c) 2025 Brianna Bailey, Daniel Branch, Aditya Acharya, Clayton Buback (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1488 Investigating the Impact of Collective Self-Esteem and Perceived Discrimination on the Symptom Profile of Depression in South Asians https://openjournals.utoledo.edu/index.php/translation/article/view/1481 Nithara Murthy Manasa Swaminathan Victoria Kelly Copyright (c) 2025 Nithara Murthy, Manasa Swaminathan, Psychology (BS); Clinical Psychology (MS), Dr. Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1481 In vitro studies of metabolic hormone signaling and central control of fertility https://openjournals.utoledo.edu/index.php/translation/article/view/1497 Luis Jaramillo Kathryn Smedlund PhD Jennifer Hill PhD Copyright (c) 2025 David, Kathryn Smedlund PhD, Jennifer Hill PhD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1497 A Functional Protein Kinase Atlas of Disorders of Cognition https://openjournals.utoledo.edu/index.php/translation/article/view/1523 Imami Ali Sajid Nicholas Henkel Priyanka Pulvender Emily Devine Benjamin Siciliano Zhexing Wen Robert Smith Copyright (c) 2025 Imami Ali Sajid, Nicholas Henkel, Priyanka Pulvender, Emily Devine, Benjamin Siciliano, Zhexing Wen, Robert Smith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1523 Mind and Spirit: Harnessing the Healing Power of Islamic-Based Interventions for Mental Health https://openjournals.utoledo.edu/index.php/translation/article/view/1494 Aylia Zahra Naqvi Agha Shahid Rida Zahra Naqvi Copyright (c) 2025 Aylia Zahra Naqvi, Agha Shahid, Rida Zahra Naqvi (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1494 Exploration of phosphatase signaling -related gene expression changes https://openjournals.utoledo.edu/index.php/translation/article/view/1527 Zayn Cheema William G. Ryan, V Ali Sajid Imami Sean Hanna Robert E. McCullumsmith Copyright (c) 2025 Zayn Cheema, William G. Ryan, V, Ali Sajid Imami, Sean Hanna, Robert E. McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1527 Recapitulation of REM sleep behavior disorder in rat model of Parkinson’s disease https://openjournals.utoledo.edu/index.php/translation/article/view/1469 Caroline Swain Khoi Le Kala Venkiteswaran Thyagarajan Subramanian Copyright (c) 2025 Caroline Swain, Khoi Le, Kala Venkiteswaran , Thyagarajan Subramanian (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1469 Gut Microbiota Modulation: Akkermansia muciniphila Lowers Blood Pressure by Restoring Serotonergic Gut-Vagal Signaling in Rodents https://openjournals.utoledo.edu/index.php/translation/article/view/1485 Hemaa Sree Kumar Sarah Alekhtiar Emily Otmanowski Adriana Alviter Plata Nicole Bearss Rohit Shukla Dhananhay Yadav Vivek Kumar Mia GB Consortium Shalini Jain Guillaume De Lartigue Jasenka Zubcevic Copyright (c) 2025 Hemaa Sree Kumar, Sarah Alekhtiar, Emily Otmanowski, Adriana Alviter Plata, Nicole Bearss, Rohit Shukla, Dhananhay Yadav, Vivek Kumar, Mia GB Consortium, Shalini Jain, Guillaume De Lartigue, Jasenka Zubcevic (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1485 Management of Severe Anorexia Nervosa: A Case Report https://openjournals.utoledo.edu/index.php/translation/article/view/1504 Nilan Mani Sabrina Khuder Jeffrey Boward Victoria Kelly Copyright (c) 2025 Nilan Mani, Sabrina Khuder, Jeffrey Boward, Victoria Kelly (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1504 Folate prevent autism-relevant phenotype from developmental pyrethroid exposure in Prarie Voles https://openjournals.utoledo.edu/index.php/translation/article/view/1524 Nilanjana Saferin Radha Shah Shah Copyright (c) 2025 Nilanjana Saferin, Radha Shah Shah (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1524 Unraveling the Gut: A Case of Adult-Onset Avoidant Restrictive Food Intake Disorder Related To Chronic GI Issues https://openjournals.utoledo.edu/index.php/translation/article/view/1492 Connor Segur Felix Griffin Blair Hermiller, MD Victoria Kelly, MD Copyright (c) 2025 Connor Segur, Felix Griffin, Blair Hermiller, MD, Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1492 Investigating the Symptom Profile of Depression and Validity of Psychological Assessments in the South Asian Population https://openjournals.utoledo.edu/index.php/translation/article/view/1480 Nithara Murthy Victoria Kelly Manasa Swaminathan Copyright (c) 2025 Nithara Murthy, Global Health (BA); Psychology (BS), Dr. Victoria Kelly, MD, Manasa Swaminathan, Psychology (BS); Clinical Psychology (MS) (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1480 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and synaptic plasticity in mouse brain https://openjournals.utoledo.edu/index.php/translation/article/view/1483 Jennifer Nguyen Melissa A. Curtis Ali S. Imami William G. Ryan Khaled Alganem Kari L. Neifer Nilanjana Saferin Charlotte N. Nawor Brian P. Kistler Gary W. Miller Rammohan Shukla Robert E. McCullumsmith James P. Burkett Copyright (c) 2025 Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith, James P. Burkett (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1483 Pathway enrichment and FDA-approved drug repurposing analysis for the treatment of CTNNB1 Syndrome modeled in an SH-SY5Y cell line https://openjournals.utoledo.edu/index.php/translation/article/view/1507 John Vergis Robert E. McCullumsmith Copyright (c) 2025 John Vergis, Robert E. McCullumsmith (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1507 When PHACES hide faces: A Case Report of PHACE Syndrome with Depression https://openjournals.utoledo.edu/index.php/translation/article/view/1490 Isaac Arefi Anish Sharma Jessica Sedlak Andrew Michaelis Navtej Mann Nilan Mani Harmandeep Pannu Tanvir Singh Copyright (c) 2025 Isaac Arefi, Anish Sharma, Jessica Sedlak, Andrew Michaelis, Navtej Mann, Nilan Mani, Harmandeep Pannu, Tanvir Singh (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1490 Naloxone Decriminalization and Opioid Overdose Trends: A Comparative Study of Lucas County, Ohio and the U.S. https://openjournals.utoledo.edu/index.php/translation/article/view/1512 Margarita Kugotova Megan Kussman Savanna King Amber Edson Mackenzie Hagood Virinder Grewal Tanvir Singh Copyright (c) 2025 Margarita Kugotova, Megan Kussman, Savanna King, Amber Edson, Mackenzie Hagood, Virinder Grewal, Tanvir Singh (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1512 I Got My Patient Arrested https://openjournals.utoledo.edu/index.php/translation/article/view/1496 Adam Koenig, MD Jack Mariani Mirlinda Elmazi, MD Asif Becher, MD Victoria Kelly, MD Copyright (c) 2025 Adam Koenig, MD, Jack Mariani, Mirlinda Elmazi, MD, Asif Becher, MD, Victoria Kelly, MD (Author) https://creativecommons.org/licenses/by/4.0 2025-10-15 2025-10-15 14 S1 10.46570/utjms-2025-1496