Targeting the gut to protect from ascending pathology in the paraquat and lectin model of Parkinson's disease

Authors

DOI:

https://doi.org/10.46570/utjms-2024-1161

Keywords:

Parkinson's, alpha-synuclein, paraquat, squalamine, Symposium

References

(1) Berry, C., La Vecchia, C., & Nicotera, P. (2010). Paraquat and Parkinson's disease. Cell Death & Differentiation, 17(7), 1115-1125.

(2) Nachbar, M. S., & Oppenheim, J. D. (1980). Lectins in the United States diet: a survey of lectins in commonly consumed foods and a review of the literature. The American journal of clinical nutrition, 33(11), 2338-2345.

(3) Baintner, K., Jakab, G., Gyôri, Z., & Kiss, P. (2000). Binding of FITC-labelled lectins to the gastrointestinal epithelium of the rat. Pathology & Oncology Research, 6, 179-183.

(4) Anselmi, L., Bove, C., Coleman, F. H., Le, K., Subramanian, M. P., Venkiteswaran, K., ... & Travagli, R. A. (2018). Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat. npj Parkinson's Disease, 4(1), 30.

(5) Perni, M., Galvagnion, C., Maltsev, A., Meisl, G., Müller, M. B., Challa, P. K., ... & Dobson, C. M. (2017). A natural product inhibits the initiation of ?-synuclein aggregation and suppresses its toxicity. Proceedings of the National Academy of Sciences, 114(6), E1009-E1017.

(6) Camilleri, M., Subramanian, T., Pagan, F., Isaacson, S., Gil, R., Hauser, R. A., ... & Barbut, D. (2022). Oral ENT-01 targets enteric neurons to treat constipation in Parkinson disease: a randomized controlled trial. Annals of internal medicine, 175(12), 1666-1674.

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Published

2024-11-21

How to Cite

1.
Swain C, Peshattiwar V, Le K, Nester I, Venkiteswaran K, Subramanian T. Targeting the gut to protect from ascending pathology in the paraquat and lectin model of Parkinson’s disease . Translation [Internet]. 2024 Nov. 21 [cited 2025 Sep. 6];13(S1). Available from: http://openjournals.utoledo.edu/index.php/translation/article/view/1161

Issue

Vol. 13 No. S1 (2024): The 2024 Department of Neurosciences and Psychiatry Research Symposium

Section

Departments of Neuroscience and Psychiatry Research Symposium

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Copyright (c) 2024 Caroline Swain, Vaibhavi Peshattiwar, Khoi Le, Isabel Nester, Kala Venkiteswaran, Thyagarajan Subramanian (Author)

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